Characterization of the HollandPTC proton therapy beamline dedicated to uveal melanoma treatment and an interinstitutional comparison

Purpose Eye dedicated proton therapy PT facilities are used to treat malignant intraocular lesions, especially uveal melanoma UM . The first commercial ocular PT beamline from Varian was installed in the Netherlands. In this work, the conceptual design of the new eyeline is presented. In addition, a comprehensive comparison against five PT centers with dedicated ocular beamlines is performed, and the clinical impact of the identified differences is analyzed. Material Methods The HollandPTC eyeline was characterized. Four centers in Europe and one in the United States joined the study. All cent... Mehr ...