Resequencing three candidate genes for major depressive disorder in a Dutch cohort
Major depressive disorder (MDD) is a psychiatric disorder, characterized by periods of low mood of more than two weeks, loss of interest in normally enjoyable activities and behavioral changes. MDD is a complex disorder and does not have a single genetic cause. In 2009 a genome wide association study (GWAS) was performed on the Dutch GAIN-MDD cohort. Many of the top signals of this GWAS mapped to a region spanning the gene PCLO, and the non-synonymous coding single nucleotide polymorphism (SNP) rs2522833 in the PCLO gene became genome wide significant after post-hoc analysis. We performed rese... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2013 |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27453089 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://repub.eur.nl/pub/62209 |