Audit on nuchal translucency thickness measurements in Flanders, Belgium: a plea for methodological standardization

Abstract Objectives To audit nuchal translucency thickness (NT) measurements for fetal aneuploidy screening in Flanders, and to estimate the impact of small variations in NT measurement on the screening result of two first‐trimester screening algorithms: maternal age + NT (Algorithm A), and maternal age + NT + pregnancy associated plasma protein‐A + free β‐human chorionic gonadotropin (Algorithm B). Methods We used the database of first‐trimester combined screening, as collected by the General Medical Laboratory AML in Antwerp, Belgium, between 1 January 2001 and 1 April 2004. Audit was perfor... Mehr ...