Mx Scripts Library: Structural Equation Modeling Scripts for Twin and Family Data
Structural equation modeling (SEM) provides a flexible tool to carry out genetic analyses of family and twin data. The basic model which decomposes the variance between and within families for a particular trait into genetic and non-genetic components can be generalized to multivariate and/ or longitudinal data, incorporate sex differences in parameter estimates, and model the effects of measured environment, candidate genes or DNA marker data. We introduce a web-based library ( http://www.psy.vu.nl/mxbib ) of scripts for uni- and multivariate genetic epidemiological analyses, as well as for l... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2005 |
Reihe/Periodikum: | Posthuma , D & Boomsma , D I 2005 , ' Mx Scripts Library: Structural Equation Modeling Scripts for Twin and Family Data ' , Behavior Genetics , vol. 35 , no. 4 , pp. 499-505 . https://doi.org/10.1007/s10519-005-2791-5 |
Schlagwörter: | /dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_ / name=Netherlands Twin Register (NTR) / /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being / name=SDG 3 - Good Health and Well-being |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-27229735 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://research.vu.nl/en/publications/97e685ce-09fd-44f0-8725-0b8054b9de72 |
Structural equation modeling (SEM) provides a flexible tool to carry out genetic analyses of family and twin data. The basic model which decomposes the variance between and within families for a particular trait into genetic and non-genetic components can be generalized to multivariate and/ or longitudinal data, incorporate sex differences in parameter estimates, and model the effects of measured environment, candidate genes or DNA marker data. We introduce a web-based library ( http://www.psy.vu.nl/mxbib ) of scripts for uni- and multivariate genetic epidemiological analyses, as well as for linkage and genetic association tests. The scripts are written to be used with the freely available software package Mx and provide a flexible and uniform approach to the analysis of data from relatives. © 2005 Springer Science+Business Media, Inc.