Natural history and screening model for high-risk human papillomavirus infection, neoplasia and cervical cancer in the Netherlands
A simulation model is presented that assumes that persistent infection with high-risk human papillomavirus (hrHPV) is a necessary cause of cervical cancer. For the estimation of the model parameters, data of recent Dutch follow-up studies were reanalyzed. The predicted incidences of cervical cancer, cervical intraepithelial neoplasia (CIN1, CIN2 and CIN3) and abnormal cytology were validated with nationwide figures and population-based screening results. The model predicted a lifetime risk for cervical cancer of 2.9% with a peak at age 48 years. The predicted lifetime risk dropped to 0.4% when... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2005 |
Reihe/Periodikum: | Berkhof , J , De Bruijne , M C , Zielinski , G D & Meijer , C J L M 2005 , ' Natural history and screening model for high-risk human papillomavirus infection, neoplasia and cervical cancer in the Netherlands ' , International Journal of Cancer , vol. 115 , no. 2 , pp. 268-275 . https://doi.org/10.1002/ijc.20846 |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26846177 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://research.vumc.nl/en/publications/d642ce61-bc16-460e-b9df-14a95dba2957 |