Chromosome 9: linkage for borderline personality disorder features.
Objective A large-scale twin study implicated genetic influences on borderline personality disorder (BPO) features, with a heritability estimate of 42%. To date, no genome-wide linkage study has been conducted to identify the genomic region(s) containing the quantitative trait loci that influence the manifestation of BPD features. Methods We conducted a family-based linkage study using Merlin regress. The participating families were drawn from the community-based Netherlands Twin Register. The sample consisted of 711 sibling pairs with phenotype and genotype data, and 561 additional parents wi... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2008 |
Reihe/Periodikum: | Distel , M A , Hottenga , J J , Trull , T J & Boomsma , D I 2008 , ' Chromosome 9: linkage for borderline personality disorder features. ' , Psychiatric Genetics , vol. 18 , no. 6 , pp. 302-307 . https://doi.org/10.1097/YPG.0b013e3283118468 |
Schlagwörter: | /dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_ / name=Netherlands Twin Register (NTR) |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26843972 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://research.vu.nl/en/publications/59097406-ca41-4468-b3fe-6e020af2feae |