Apolipoprotein E and Carotid Artery Atherosclerosis. The Rotterdam Study

BACKGROUND AND PURPOSE: Carotid artery atherosclerosis is a strong predictor for future stroke. It is yet unclear whether the apolipoprotein E polymorphism (APOE) is related to atherosclerosis in the carotid arteries. The aim of the present study was to investigate the role of APOE in carotid artery atherosclerosis. METHODS: A population-based cross-sectional study was performed on 5401 subjects. Atherosclerosis was noninvasively assessed by the common carotid artery intima-media wall thickness and the presence of plaques in the carotid arteries. The relationship of the 6 APOE genotypes with t... Mehr ...

Verfasser: Slooter, A.J.C. (Arjen)
Bots, M.L. (Michiel)
Havekes, L.M.
Sol, A.I. (Antonio Iglesias)
Cruts, M. (Marc)
Grobbee, D.E. (Diederick)
Hofman, A. (Albert)
Broeckhoven, C. (Christine) van
Duijn, C.M. (Cornelia) van
Witteman, J.C.M. (Jacqueline)
Dokumenttyp: Artikel
Erscheinungsdatum: 2001
Schlagwörter: 0 (Apolipoproteins E) / 0 (Lipoproteins / HDL Cholesterol) / 57-88-5 (Cholesterol) / Aged / Apolipoproteins E/blood/*genetics / Carotid Artery Diseases/blood/diagnosis/*epidemiology / Carotid Artery / Common/ultrasonography / Cholesterol/blood / Cohort Studies / Cross-Sectional Studies / Female / Genotype / Human / Lipoproteins / HDL Cholesterol/blood / Male / Middle Aged / Netherlands/epidemiology / Odds Ratio / Polymorphism (Genetics) / Prevalence / Support / Non-U.S. Gov't / Tunica Intima/ultrasonography / Tunica Media/ultrasonography / atherosclerosis / stroke
Sprache: Englisch
Permalink: https://search.fid-benelux.de/Record/base-26832895
Datenquelle: BASE; Originalkatalog
Powered By: BASE
Link(s) : http://repub.eur.nl/pub/5981