P26 Pilot on harmonising dosing recommendation for term and preterm neonates in the Netherlands (Neodose project)

Background Many drugs are used off-label in term and preterm neonates, and dosing recommendations for many drugs are lacking in the Dutch Paediatric Formulary (DPF). This results in widely varying dosing regimens used across neonatal intensive care units (NICUs) in the Netherlands. The Neodose pilot project aimed to develop best-evidence national dosing recommendations for (pre)term neonates. Because scientific evidence is scarce, a consensus-based approach was used. Methods A priority drug list, containing the most frequently used drugs for neonates, was drafted. From this list 22 drugs were... Mehr ...