Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer: Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses
Background Observational studies examining associations between adult height and risk of colorectal, prostate, and lung cancers have generated mixed results. We conducted meta-analyses using data from prospective cohort studies and further carried out Mendelian randomization analyses, using height-associated genetic variants identified in a genome-wide association study (GWAS), to evaluate the association of adult height with these cancers. Methods and Findings A systematic review of prospective studies was conducted using the PubMed, Embase, and Web of Science databases. Using meta-analyses,... Mehr ...
Verfasser: |
Khankari, NK
Shu, X-O
Wen, W
Kraft, P
Lindstrom, S
Peters, U
Schildkraut, J
Schumacher, F
Bofetta, P
Risch, A
Bickeboeller, H
Amos, CI
Easton, D
Eeles, RA
Gruber, SB
Haiman, CA
Hunter, DJ
Chanock, SJ
Pierce, BL
Zheng, W |
Dokumenttyp: |
Journal article |
Erscheinungsdatum: |
2016 |
Verlag/Hrsg.: |
PUBLIC LIBRARY OF SCIENCE
|
Schlagwörter: |
Science & Technology
/ Life Sciences & Biomedicine
/ Medicine
/ General & Internal
/ General & Internal Medicine
/ BODY-MASS-INDEX
/ DIFFERENT ANATOMIC SITES
/ GROWTH-FACTOR (IGF)-I
/ IGF-BINDING PROTEINS
/ FOLLOW-UP
/ NORWEGIAN MEN
/ RECTAL-CANCER
/ NETHERLANDS COHORT
/ JAPANESE MEN
/ OLDER WOMEN
/ Adult
/ Aged
/ 80 and over
/ Body Height
/ Colorectal Neoplasms
/ Female
/ Genetic Variation
/ Genome-Wide Association Study
/ Humans
/ Lung Neoplasms
/ Male
/ Mendelian Randomization Analysis
/ Middle Aged
/ Odds Ratio
/ Prospective Studies
/ Prostatic Neoplasms
/ Risk Factors
/ Young Adult
/ Colorectal Transdisciplinary Study (CORECT)
/ Discovery
/ Biology
/ and Risk of Inherited Variants in Breast Cancer (DRIVE)
/ Elucidating Loci Involved in Prostate Cancer Susceptibility (ELLIPSE)
/ Transdisciplinary Research in Cancer of the Lung (TRICL) |
Sprache: |
Englisch |
Permalink: |
https://search.fid-benelux.de/Record/base-26808162 |
Datenquelle: |
BASE;
Originalkatalog |
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BASE |
Link(s) :
|
http://hdl.handle.net/10044/1/60983 |