Seasonal variation of <scp>anti‐PD</scp>‐1 outcome in melanoma—Results from a Dutch patient cohort
Abstract Despite the improved survival rates of patients with advanced stage melanoma since the introduction of ICIs, many patients do not have (long‐term) benefit from these treatments. There is evidence that the exposome, an accumulation of host‐extrinsic factors including environmental influences, could impact ICI response. Recently, a survival benefit was observed in patients with BRAF wild‐type melanoma living in Denmark who initiated immunotherapy in summer as compared to winter. As the Netherlands lies in close geographical proximity to Denmark and has comparable seasonal differences, a... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2023 |
Reihe/Periodikum: | Pigment Cell & Melanoma Research ; volume 37, issue 1, page 15-20 ; ISSN 1755-1471 1755-148X |
Verlag/Hrsg.: |
Wiley
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Schlagwörter: | Dermatology / General Biochemistry / Genetics and Molecular Biology / Oncology |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26690860 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | http://dx.doi.org/10.1111/pcmr.13117 |