Heritability and Genome-Wide Association Studies for Hair Color in a Dutch Twin Family Based Sample
Hair color is one of the most visible and heritable traits in humans. Here, we estimated heritability by structural equation modeling (N = 20,142), and performed a genome wide association (GWA) analysis (N = 7091) and a GCTA study (N = 3340) on hair color within a large cohort of twins, their parents and siblings from the Netherlands Twin Register (NTR). Self-reported hair color was analyzed as five binary phenotypes, namely “blond versus non-blond”, “red versus non-red”, “brown versus non-brown”, “black versus non-black”, and “light versus dark”. The broad-sense heritability of hair color was... Mehr ...
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Dokumenttyp: | Artikel |
Erscheinungsdatum: | 2015 |
Reihe/Periodikum: | Lin , B , Mbarek , H , Willemsen , G , Dolan , C V , Fedko , I O , Abdellaoui , A , de Geus , E J C , Boomsma , D I & Hottenga , J J 2015 , ' Heritability and Genome-Wide Association Studies for Hair Color in a Dutch Twin Family Based Sample ' , Genes , vol. 6 , no. 3 , pp. 559-576 . https://doi.org/10.3390/genes6030559 |
Schlagwörter: | /dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_ / name=Netherlands Twin Register (NTR) |
Sprache: | Englisch |
Permalink: | https://search.fid-benelux.de/Record/base-26686572 |
Datenquelle: | BASE; Originalkatalog |
Powered By: | BASE |
Link(s) : | https://research.vu.nl/en/publications/365b7c94-3671-456e-aa30-f0675347ad82 |