Activating transcription factor 6 polymorphisms and haplotypes are associated with impaired glucose homeostasis and type 2 diabetes in Dutch Caucasians
CONTEXT: Activating transcription factor 6 (ATF6) is critical for initiation and full activation of the unfolded protein response. An association between genetic variation in ATF6 and type 2 diabetes (DM2) was recently reported in Pima Indians. OBJECTIVES: To investigate the broader significance of this association for DM2, replication studies in distinct ethic populations are required. We investigated ATF6 for its association with DM2 in Dutch Caucasians. DESIGN/SETTING: A genetic association study was conducted at an academic research laboratory. STUDY PARTICIPANTS: Two independent Dutch coh... Mehr ...
| Verfasser: |
Meex, S.J.
van Greevenbroek, M.M.J.
Ayoubi, T.A.
Vlietinck, R.
van Vliet-Ostaptchouk, J.V.
Hofker, M.H.
Vermeulen, V.M.
Schalkwijk, C.G.
Feskens, E.J.
Boer, J.M.
Stehouwer, C.D.
van der Kallen, C.J.H.
de Bruin, T.W. |
| Dokumenttyp: |
Artikel |
| Erscheinungsdatum: |
2007 |
| Reihe/Periodikum: |
Meex , S J , van Greevenbroek , M M J , Ayoubi , T A , Vlietinck , R , van Vliet-Ostaptchouk , J V , Hofker , M H , Vermeulen , V M , Schalkwijk , C G , Feskens , E J , Boer , J M , Stehouwer , C D , van der Kallen , C J H & de Bruin , T W 2007 , ' Activating transcription factor 6 polymorphisms and haplotypes are associated with impaired glucose homeostasis and type 2 diabetes in Dutch Caucasians ' , Journal of Clinical Endocrinology & Metabolism , vol. 92 , no. 7 , pp. 2720-2725 . https://doi.org/10.1210/jc.2006-2280 |
| Sprache: |
Englisch |
| Permalink: |
https://search.fid-benelux.de/Record/base-26664722 |
| Datenquelle: |
BASE;
Originalkatalog |
| Powered By: |
BASE |
| Link(s) :
|
https://cris.maastrichtuniversity.nl/en/publications/ea984f62-2689-4404-9a11-d28e722ac5ce |
